Reaktion #58543

Reaktionsgleichung

product

1-Benzyl-4-thiophen-3-yl-piperidine-3-carboxylic acid ethyl ester

HCl

→

subtitle compound

1-Benzyl-4-thiophen-3-yl-piperidine-3-carboxylic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeNext, the reaction was evaporated to dryness, azeotrope with toluene (2×50 ml)

Vorschrift

The product from step c) (4.5 g, 13.7 mmol) was treated with 4 M HCl at 1000C for 16 hours. Next, the reaction was evaporated to dryness, azeotrope with toluene (2×50 ml) and placed on the high vacuum to give the subtitle compound that was used without further purification. MS calculated for C17H19NO2S−H 300, observed 300.

Quelle