Reaktion #583965

Reaktionsgleichung

3-Methoxypiperonal

nitromethane

ammonium acetate

→

yellow solid

4-Methoxy-6-(2-nitrovinyl)-1,3-benzodioxole

Lösungsmittel

acetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeSolvents are removed in vacuo
2. 2
   FiltrationThe solution is filtered
3. 3
   Waschenthe filtrate is washed with water

Vorschrift

3-Methoxypiperonal (50.0 g) is combined with 71.9 mL of nitromethane in 250 mL of acetic acid; 36 g of ammonium acetate is added, and the mixture is heated to 50° C. for 4 hrs. Solvents are removed in vacuo; the residue is taken up in water and stirred for 20 min. The solution is filtered; the filtrate is washed with water, then ether, to give 51.8 g of a yellow solid.

Quelle