Reaktion #582285

Reaktionsgleichung

4d

2-adamantan-1-yl-(4R)-[2-(diphenyl-phosphinothioyl)-phenyl]-4,5-dihydro-oxazole

→

2-tert-Butyl-(4R)-[2-(dicyclohexyl-phosphinothioyl)-phenyl]-4,5-dihydro-oxazole

Lösungsmittel

CHCl3

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was produced by the same method

Vorschrift

This compound was produced by the same method used for 4d as a colorless oil (52%). [α]20D=−78.0 (c=0.50, CHCl3); 1H NMR (CDCl3, 300 MHz) 6 7.54-7.49 (m, 2H), 7.37-7.31 (m, 2H), 6.53 (m, 1H), 4.94 (t, J=9.5 Hz, 1H), 3.92 (t, J=8.0 Hz, 1H), 2.54 (m, 1H), 2.31 (m, 1H), 2.09 (m, 1H), 1.91-1.13 (m, 19H), 1.34 (s, 9H); 13C NMR (CDCl3, 75 MHz) δ 175.7, 149.2, 131.7 (d, J=2.6 Hz), 131.3, 128.6 (d, J=9.0 Hz), 126.3 (d, J=10.5 Hz), 125.0 (d, J=63.8 Hz), 76.2, 66.5 (d, J=3.7 Hz), 41.2 (d, J=48.2 Hz), 36.5 (d, J=51.2 Hz), 33.3, 27.9, 26.6-25.2 (m); 31P NMR (CDCl3, 145 MHz) δ 57.27 (br); HRMS (M++1) m/z calculated for C25H39NOPS 432.24845, found 432.24619.

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