Reaktion #581950

Reaktionsgleichung

product

2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl methanesulfonate

3-(S)-(dimethylamino)pyrrolidine

→

titled compound

4-(2-{2-[(3S)-3-(dimethylamino)pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile

Reaktionsbedingungen

Vorschrift

The product from Example 1C and 3-(S)-(dimethylamino)pyrrolidine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.88 (m, 1H), 7.80 (m, 4H), 7.58 (m, 2H), 6.80 (s, 1H), 4.43 (m, 1H), 3.6-3.9 (m, 4H), 3.35-3.45 (m, 4H), 2.95 (s, 6H), 2.6 (m, 1H), 2.35 (m, 1H); MS (DCI) m/z 360 (M+H)+;

Quelle