Reaktion #58087

ord-21fdd7ff3f3e42a58164f406b88f15bb

Reaktionsgleichung

NNC(=O)c1ccc(C(F)(F)F)cc1
4-(trifluoromethyl)benzoic acid hydrazide
CCOC(C)=N.Cl
ethyl acetimidate hydrochloride
→
CC(=N)NNC(=O)c1ccc(C(F)(F)F)cc1
4-trifluoromethyl-benzoic acid N′-(1-imino-ethyl)-hydrazide

Edukte

NNC(=O)c1ccc(C(F)(F)F)cc1
4-(trifluoromethyl)benzoic acid hydrazide
CCOC(C)=N.Cl
ethyl acetimidate hydrochloride
—
product 1a

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

4.78 g (23.4 mmol) 4-(trifluoromethyl)benzoic acid hydrazide and 5.21 g (42.1 mmol) ethyl acetimidate hydrochloride are reacted as described for intermediate product 1a).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07423036B2uspto-grants-2008_09