Reaktion #57869

Reaktionsgleichung

(2-Amino-5-chloro-phenyl)-(2-methyl-pyridin-4-yl)-methanone

4-trifluoromethoxy-benzenesulfonyl chloride

→

title compound

N-[4-Chloro-2-(2-methyl-pyridine-4-carbonyl)-phenyl]-4-trifluoromethoxy-benzenesulfonamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified by HPLC

Vorschrift

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-Amino-5-chloro-phenyl)-(2-methyl-pyridin-4-yl)-methanone and 4-trifluoromethoxy-benzenesulfonyl chloride and purified by HPLC. 1H NMR (CDCl3) δ 10.17(s, 1H) 8.63 (d, J=4 Hz, 1H) 7.78 (m, 3H) 7.51 (s, 1H) 7.30 (s, 1H) 7.17 (s, 1H) 7.09 (s, 1H) 6.97 (d, J=4 Hz, 2H) 2.64 (s, 3H). MS (ES) m/z=471.0 (M++1).

Quelle