Reaktion #57851

Reaktionsgleichung

(2-Amino-5-chloro-phenyl)-(2-chloro-pyridin-4-yl)-methanone

4-tert-Butyl-benzenesulfonyl chloride

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title compound

4-tert-butyl-N-[4-chloro-2-(2-chloro-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide

Reaktionsbedingungen

Vorschrift

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 133 mg of (2-Amino-5-chloro-phenyl)-(2-chloro-pyridin-4-yl)-methanone and 116 mg of 4-tert-Butyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 1.26 (s, 9H), 7.18 (dd, 5.2 Hz, 1.6 Hz), 7.25 (m, 1H), 7.32 (m, 1H), 7.41 (d, 2H, J=6.4 Hz), 7.54 (dd,1H, J=9.2 Hz, 2.4 Hz), 7.67 (m, 2H), 7.77 (d,1H, J−8.8 Hz), 8.55 (d, 1H, J=5.2 Hz), 10.09 (s, 1H). MS: m/z463.0 (M++1).

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