Reaktion #577260

Reaktionsgleichung

1-ethyl-4-(5-nitro-pyridin-2-yl)-piperazine

hydrogen

→

title compound

Ausbeute 102.8%

6-(4-Ethyl-piperazin-1-yl)-pyridin-3-ylamine

Ausbeute 102.8%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter filtration the mixture
2. 2
   Sonstigewas evaporated to dryness

Vorschrift

A mixture of 2.47 g (10 mmol) 1-ethyl-4-(5-nitro-pyridin-2-yl)-piperazine and 0.247 g Pd/C (10%) in 25 ml methanol was treated with 1 bar hydrogen at room temperature for 2 h. After filtration the mixture was evaporated to dryness to yield 2.12 g (98%) of the title compound as colorless solid. (m/e): 207.3 (MH+; 100%).

Quelle