Reaktion #576250

Reaktionsgleichung

benzyl 3-(N-FMOC-L-valyloxy)-2-stearoyloxypropionate

→

3-(N-FMOC-L-valyloxy )-2-stearoyloxypropionic acid

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe catalyst was filtered
2. 2
   Waschenwashed with ethyl acetate and 1,4-dioxane
3. 3
   SonstigeThe solution was evaporated under reduced pressure

Vorschrift

A solution of benzyl 3-(N-FMOC-L-valyloxy)-2-stearoyloxypropionate (0.78 g, 1 mmole) in 20 ml ethyl acetate was hydrogenated with 10% palladium on charcoal (0.2 g) at normal pressure for three hours at room temperature. The catalyst was filtered and washed with ethyl acetate and 1,4-dioxane. The solution was evaporated under reduced pressure. Yield: 0.63 g=90%

Quelle