Reaktion #57533

ord-a588b0422ee0410ab0ab9e31a6bd2112

Reaktionsgleichung

Cc1c(C(=O)c2ccc(Cl)cc2Cl)oc2cc(Br)ccc12
(6-Bromo-3-methyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone
COC(C)=O
acetic acid methyl ester
COC(=O)Cc1cccc(-c2ccc3c(C)c(C(=O)c4ccc(Cl)cc4Cl)oc3c2)c1
{3-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-phenyl}-acetic acid methyl ester

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

{3-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-phenyl}-acetic acid methyl ester was prepared via a Suzuki coupling of (6-Bromo-3-methyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone and 3-Bromo-phenyl)-acetic acid methyl ester as described in method 1 step 5. MS ES (MH+)453.1, RT=4.27 min).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07420066B2uspto-grants-2008_09