Reaktion #574768

Reaktionsgleichung

1-benzyl-imidazole

formaldehyde

sodium hydroxide

→

1-benzyl-2-hydroxymethyl-imidazole

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis refluxed for 7 days
2. 2
   Extraktionis extracted with ethylacetate
3. 3
   EinengenConcentration in vacuo

Vorschrift

A mixture of 1-benzyl-imidazole (5 g, 32 mmol), formaldehyde 37% (10 ml, 134 mmol) and sodium hydroxide (100 mg) is refluxed for 7 days and is extracted with ethylacetate. Concentration in vacuo yields 1-benzyl-2-hydroxymethyl-imidazole.

Quelle