Reaktion #572116

Reaktionsgleichung

2,2,6,6-tetramethyl-4-piperidone

butylamine

→

desired product

4-Butylamino-2,2,6,6-tetramethylpiperidine

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter completion of the reaction
2. 2
   Filtrationthe platinum catalyst was filtered off
3. 3
   workup.DISTILLATIONthe solvent was distilled from the filtrate under reduced pressure
4. 4
   workup.DISTILLATIONThe residue was purified by vacuum distillation

Vorschrift

2.0 g of platinum oxide were added to a solution of 155 g of 2,2,6,6-tetramethyl-4-piperidone and 80 g of butylamine in 300 ml of methanol. The resulting mixture was then hydrogenated under a hydrogen atmosphere in a Parr hydrogenation apparatus at room temperature for 5 hours. After completion of the reaction, the platinum catalyst was filtered off and the solvent was distilled from the filtrate under reduced pressure. The residue was purified by vacuum distillation, to give the desired product as an oil, boiling at 100°-101° C./5 mmHg (667 Pascals).

Quelle