Reaktion #571507

Reaktionsgleichung

3,4-Methylenedioxyphenylacetic acid

lithium aluminium hydride

→

title compound

Ausbeute 90.4%

3,4-Methylenedioxyphenethyl alcohol

Ausbeute 90.4%

Lösungsmittel

ether

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooled
2. 2
   Sonstigequenched by the cautious addition of saturated aqueous ammonium chloride solution
3. 3
   Filtrationfiltered
4. 4
   WaschenThe filtrate was washed with 10% aqueous sodium carbonate solution
5. 5
   Trocknendried over magnesium sulphate
6. 6
   Sonstigeevaporated

Vorschrift

3,4-Methylenedioxyphenylacetic acid (18.0 g) was added portionwise over 30 minutes to a stirred, ice-cooled suspension of lithium aluminium hydride (4.0 g) in ether (400 ml) and the mixture was stirred at room temperature for two hours, quenched by the cautious addition of saturated aqueous ammonium chloride solution and filtered. The filtrate was washed with 10% aqueous sodium carbonate solution, dried over magnesium sulphate and evaporated to give the title compound as a pale yellow oil (15.01 g, 90%), which was characterized by its 1H-n.m.r. spectrum.

Quelle