Reaktion #571165

Reaktionsgleichung

3-phenylphenol

methyl bromoacetate

potassium carbonate

→

methyl (3-phenylphenoxy)acetate

Lösungsmittel

DMF

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted with ether
2. 2
   WaschenThe combined organic layers were washed with aqueous sodium carbonate
3. 3
   Sonstigedried
4. 4
   Filtrationfiltered
5. 5
   Sonstigeevaporated

Vorschrift

A mixture of 3-phenylphenol (5.00 g), methyl bromoacetate (3.1 ml) and potassium carbonate (8.1 g) in DMF was stirred at room temperature. After five hours, the reaction mixture was diluted with water (100 ml) and then extracted with ether. The combined organic layers were washed with aqueous sodium carbonate followed by brine and then dried, filtered and evaporated to give crude methyl (3-phenylphenoxy)acetate (7.2 g) as a pale yellow liquid, 1H NMR (CDCl3) delta 3.8 (3H,s), 4.7 (2H,s), 6.8-7.6 (9H,m) ppm.

Quelle