Reaktion #570152

ord-a76a9e7bad3d40479e682b9c4056a987

Reaktionsgleichung

Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.Cl.[Cl-]
thiamine hydrochloride
CC1(S(=O)(=O)[O-])CC(=O)c2ccccc2C1=O.[Na+]
sodium menadione bisulfite
→
CC1(S(=O)(=O)O)CC(=O)c2ccccc2C1=O.Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Menadione bisulfite thiamine

Edukte

Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.Cl.[Cl-]
thiamine hydrochloride
CC1(S(=O)(=O)[O-])CC(=O)c2ccccc2C1=O.[Na+]
sodium menadione bisulfite

Reagenzien

Keine

Lösungsmittel

O
water

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.ADDITIONwas added within about half an hour
  2. 2
    workup.WAITAfter half an hour of agitation
  3. 3
    Sonstigeto precipitate
  4. 4
    workup.WAITAfter an hour
  5. 5
    Filtrationthe precipitate was filtered
  6. 6
    Waschenwashed
  7. 7
    Sonstigedried
  8. 8
    Sonstigewas obtained

Vorschrift

25 g of thiamine hydrochloride (vitamin B1) was dissolved in 50 g of water; to said solution of 25 g of powdery sodium menadione bisulfite was added within about half an hour. After half an hour of agitation, the reaction mass became opalescent and the adduct began to precipitate. After an hour, the precipitate was filtered, washed and dried. 25 g of a white product having the following analysis was obtained.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04577019uspto-grants-1986_03