Reaktion #56839

Reaktionsgleichung

4-chloro-6-(5-chloro-2-methyl-phenyl)-2-methyl-pyrimidine

4-chloroaniline

→

title compound

Ausbeute 97.0%

[6-(5-Chloro-2-methyl-phenyl)-2-methyl-pyrimidin-4-yl]-(4-chloro-phenyl)-amine

Ausbeute 97.0%

Reaktionsbedingungen

Vorschrift

Following the method described in Example 38 (alternate method), 4-chloro-6-(5-chloro-2-methyl-phenyl)-2-methyl-pyrimidine and 4-chloroaniline provided the title compound (97% yield). 1H NMR (DMSO-d6) δ 2.35 (s, 3H, CH3), 2.53 (s, 3H, CH3), 6.71 (s, 1H, Ar), 7.35-7.44 (m, 4H, Ar), 7.49 (d, 1H, J=2.2 Hz, Ar), 7.78 (d, 1H, J=8.8 Hz, Ar), 9.72 (s, 1H, NH).

Quelle