Reaktion #566669

ord-c9157a86b4ed409d9595a9d8e0593589

Reaktionsgleichung

CC[C@H](C)[C@H](N)C(=O)O
(L)-Isoleucine
Cc1ccc(C(=O)Cl)cc1
p-toluoyl chloride
→
CC[C@@H](C)[C@@H](NC(=O)c1ccc(C)cc1)C(=O)O
desired product
CC[C@@H](C)[C@@H](NC(=O)c1ccc(C)cc1)C(=O)O
(2R,3R)-3-methyl-2-((4-methylbenzoyl)amino)pentanoic Acid

Edukte

CC[C@H](C)[C@H](N)C(=O)O
(L)-Isoleucine
Cc1ccc(C(=O)Cl)cc1
p-toluoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

(L)-Isoleucine and p-toluoyl chloride were processed as described in Example 26A to provide the desired product.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06645968B2uspto-grants-2003_11