Reaktion #565304

Reaktionsgleichung

trans-1,4-cyclohexane dimethanol

N-methyl morpholine

hexyl phosphoro-dichloridate

→

CHDM

Lösungsmittel

methylene chloride

methylene chloride

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeequipped with a funnel
2. 2
   Sonstigeto flush through the funnel
3. 3
   Sonstigewas then brought up to room temperature
4. 4
   workup.STIRRINGkept stirring for four hours

Vorschrift

Under an argon stream, 10 g of trans-1,4-cyclohexane dimethanol (CHDM), 15.25 mL (14.03 g) of N-methyl morpholine (NMM), and 50 mL of methylene chloride were transferred into a 250 mL flash equipped with a funnel. The solution in the flask was cooled down to −40° C. with stirring. A solution of 15.19 g of hexyl phosphoro-dichloridate (HOP) in 20 mL of methylene chloride was added through the funnel, and an additional 10 mL of methylene chloride was used to flush through the funnel. The mixture was then brought up to room temperature gradually and kept stirring for four hours.

Quelle