Reaktion #565300

Reaktionsgleichung

6-N-benzyloxycarbonyl-L-lysine

trifluoroacetic acid ethyl ester

→

2-N-Trifluoroacetyl-6-N-benzyloxycarbonyl-L-lysine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeIt is evaporated to the dry state
2. 2
   Sonstigethe residue is crystallized from diisopropyl ether

Vorschrift

100.0 g (356.7 mmol) of 6-N-benzyloxycarbonyl-L-lysine is dissolved in a mixture that consists of 1000 ml of trifluoroacetic acid ethyl ester and 500 ml of ethanol, and it is stirred for 24 hours at room temperature. It is evaporated to the dry state, and the residue is crystallized from diisopropyl ether.

Quelle