Reaktion #565293

Reaktionsgleichung

N-(1-methylhexyl)aniline

1-bromobutane

potassium carbonate

DMF

1-bromo butane

→

N-butyl-N-(1-methylhexyl)aniline

Ausbeute 44.0%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhile heating
2. 2
   Temperaturunder reflux for 41 hours
3. 3
   workup.STIRRINGthe mixture stirred
4. 4
   Temperaturwhile heating
5. 5
   Temperaturunder reflux for a further 19 hours
6. 6
   Sonstigethe organic phase separated
7. 7
   ExtraktionThe aqueous phase was extracted with toluene
8. 8
   Extraktionthe organic phases and toluene extract
9. 9
   Waschenwashed with water (2×100 parts)
10. 10
    Sonstigebefore evaporating

Vorschrift

A mixture of N-(1-methylhexyl)aniline (76 parts), 1-bromobutane (66 parts), anhydrous potassium carbonate (65 parts) and DMF (150 parts) was stirred while heating under reflux for 41 hours. An additional quantity of 1-bromo butane (44 parts) was added and the mixture stirred while heating under reflux for a further 19 hours. The cooled mixture was poured into water (400 parts) and the organic phase separated. The aqueous phase was extracted with toluene, the organic phases and toluene extract were combined and washed with water (2×100 parts) before evaporating to leave N-butyl-N-(1-methylhexyl)aniline (72.8 parts, 44%) which was purified by vacuum distillation to give N-butyl-N-(1-methylhexyl)aniline b.pt 73-80° C., 2.6 mm Hg. [Dye (1)].

Quelle