Reaktion #564308

Reaktionsgleichung

2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine

4-hydroxyphenyl-propan-2-one

→

N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigefollowed by purification of the base on a silica gel column

Vorschrift

Prepared by analogy to Example 13 by reaction of 2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine with 4-hydroxyphenyl-propan-2-one followed by purification of the base on a silica gel column using chloroform/methanol=9:1 as eluant.

Quelle