Reaktion #56402

Reaktionsgleichung

4-methylbenzenesulfonic acid

1-(phenylmethyl)-4-piperidinone

3-pyridinamine

methylbenzene

→

N-[1-(phenylmethyl)-4-piperidinylidene]-3-pyridinamine

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturrefluxed for 5 hours
2. 2
   Sonstige(The reaction vessel is provided
3. 3
   Temperaturwith reflux-condensor
4. 4
   SonstigeAfter the calculated amount of water is separated
5. 5
   Sonstigethe solvent is evaporated
6. 6
   workup.DISSOLUTIONThe oily residue is dissolved in 800 parts of 2,2'-oxybispropane
7. 7
   Sonstigeevaporated again

Vorschrift

A mixture of 19 parts of 1-(phenylmethyl)-4-piperidinone, 11.8 parts of 3-pyridinamine, 120 parts of methylbenzene and a small volume of 4-methylbenzenesulfonic acid is stirred and refluxed for 5 hours. (The reaction vessel is provided with reflux-condensor and water-separator). After the calculated amount of water is separated, the solvent is evaporated. The oily residue is dissolved in 800 parts of 2,2'-oxybispropane and evaporated again, yielding 27 parts of N-[1-(phenylmethyl)-4-piperidinylidene]-3-pyridinamine as a yellow-brown oil.

Quelle