Reaktion #56398

Reaktionsgleichung

3,5-bis-trifluoromethyl-aniline

chloroacetyl isocyanate

→

N-(3,5-bis-trifluoromethylphenyl)-N'-(chloroacetyl)-urea

Ausbeute 74.6%

Lösungsmittel

toluene

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooled to room temperature
2. 2
   SonstigeThe product which had precipitated
3. 3
   Filtrationwas filtered off
4. 4
   Waschenrinsed with toluene/ligroin 1:2
5. 5
   Sonstigedried

Vorschrift

22.9 g (0.1 mol) of 3,5-bis-trifluoromethyl-aniline were dissolved in 150 ml of dry toluene. 11.9 g (0.1 mol) of chloroacetyl isocyanate in 50 ml of dry toluene were added. The mixture was stirred at 50° C. for 1 hour and then cooled to room temperature. The product which had precipitated was filtered off and rinsed with toluene/ligroin 1:2 and then dried. 26 g (74.5% of theory) of N-(3,5-bis-trifluoromethylphenyl)-N'-(chloroacetyl)-urea with a melting point of 170° C. were thus obtained.

Quelle