Reaktion #563516

Reaktionsgleichung

4-methoxyphenylmagnesium bromide

THF

4-methoxyphenylmagnesium bromide

4-Bromophenethyl bromide

THF

→

title compound

4-(4-Bromophenethyl)-1-methoxybenzene

Lösungsmittel

hexane ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigematerials, and reacted as in Entry 1

Vorschrift

4-Bromophenethyl bromide (261.4 mg, 1.0 mmol) and a THF solution (1.42 mL, 1.06 M, 1.5 mmol) of 4-methoxyphenylmagnesium bromide were used as starting materials, and reacted as in Entry 1. Conditions: The THF solution of 4-methoxyphenylmagnesium bromide was added dropwise at 40° C. over 3 hours. After thin-layer chromatography (hexane/ethyl acetate=92/8), the title compound was obtained as a colorless liquid (0.226 g, yield 78%).

Quelle