Reaktion #56319

Reaktionsgleichung

2-Methoxyaniline

sodium carbonate

2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane

→

N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeequipped with a mechanical stirrer
2. 2
   Temperaturthermometer and reflux condenser
3. 3
   Temperaturthe reaction mixture is heated
4. 4
   Temperaturat reflux for a period of about 1 hour
5. 5
   FiltrationAfter this time the reaction mixture is filtered
6. 6
   workup.ADDITIONadditional sodium carbonate (5 grams) is added to the filtrate
7. 7
   workup.DISTILLATIONThe mixture is then distilled under reduced pressure

Vorschrift

2-Methoxyaniline (0.05 mole) and sodium carbonate (30 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2-Bromomethyl-4-methyl-5-ethyl-1,3-dioxolane (0.55 mole) is slowly added and the reaction mixture is heated at reflux for a period of about 1 hour. After this time the reaction mixture is filtered and additional sodium carbonate (5 grams) is added to the filtrate. The mixture is then distilled under reduced pressure to yield the desired product N-(4-methyl-5-ethyl-1,3-dioxolan-2-ylmethyl)-2-methoxyaniline.

Quelle