Reaktion #56171

Reaktionsgleichung

3-chloro-6-pyridazinyl-hydrazine

3-iminobutyronitrile

→

3-chloro-6-(3-methyl-5-amino-1-pyrazolyl)-pyridazine

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturto reflux for 9 hours
3. 3
   TemperaturAfter cooling the separated crystals
4. 4
   Filtrationare filtered
5. 5
   Waschenwashed with ethanol
6. 6
   Sonstigedried

Vorschrift

A mixture of 14.5 g (0.1 moles) of 3-chloro-6-pyridazinyl-hydrazine, 8.5 g (0.1 moles) of 3-iminobutyronitrile and 150 ml of ethanol is heated to reflux for 9 hours. After cooling the separated crystals are filtered, washed with ethanol and dried. Yield: 15.6 g (74.0%); m.p.: 148°-150° C. The hydrochloride melts at 157°-159° C.

Quelle