Reaktion #55944

Reaktionsgleichung

cyclohexane carboxylic acid

N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide

LiI.2H2O

→

compound

N-(5-Phenyl-2-thienyl)cyclohexane carboxamide

Lösungsmittel

collidine

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound was also prepared

Vorschrift

This compound (m.p. 174° C.) was prepared from N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide (31.1 g, 0.1 mole) and LiI.2H2O (48.1 g, 0.32 mole) by refluxing in collidine (125 ml.) according to the procedure of Example 53 (a). This compound was also prepared according to the procedure of Example 53(b), using cyclohexane carboxylic acid as the acylating agent. The products of the two processes were spectrally identical and had a melting point of 175° C.

Quelle