Reaktion #5589

Reaktionsgleichung

title compound

N,N-dicyclohexyl-2-propenamide

2,6-bis(1,1-dimethylethyl)-4-mercaptophenol

triethylamine

→

3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N,N-dicyclohexylpropanamide

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was removed in vacuo on a rotary evaporator
2. 2
   Sonstigethe crude material purified by chromatography on silica
3. 3
   Sonstigerecrystallized from hexane, m.p. ca. 168.5°-172° C.

Vorschrift

The title compound of Example 3 (1.9 g, 0.008 mole), 2,6-bis(1,1-dimethylethyl)-4-mercaptophenol(2 g, 0.008 mole) and triethylamine (0.5 ml) were stirred in methanol (25 ml) for about 12 hours. The solvent was removed in vacuo on a rotary evaporator, the crude material purified by chromatography on silica and recrystallized from hexane, m.p. ca. 168.5°-172° C.

Quelle