Reaktion #558883

ord-9824a3a14b184a538bb8d7ba6748a9b6

Reaktionsgleichung

CCC(=O)NCC(C)(C)CO
N-(3-hydroxy-2,2-dimethylpropyl)propionamide
N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile
→
CCC(=O)NCC(C)(C)COc1cccc([N+](=O)[O-])c1C#N
N-(3-(2-cyano-3-nitrophenoxy)-2,2-dimethylpropyl)propionamide
Ausbeute 68.0%

Edukte

CCC(=O)NCC(C)(C)CO
N-(3-hydroxy-2,2-dimethylpropyl)propionamide
N#Cc1c([N+](=O)[O-])cccc1[N+](=O)[O-]
2,6-dinitrobenzonitrile

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared as in Example 215c from N-(3-hydroxy-2,2-dimethylpropyl)propionamide (Example 226c) and 2,6-dinitrobenzonitrile in 68% yield. MS 306 (MH+).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08633186B2uspto-grants-2014_01