Reaktion #55657

Reaktionsgleichung

3-nitro-4-chloro-benzophenone

N-methyl-N-octylamine

→

3-nitro-4-(N-methyl-N-octylamino)-benzophenone

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONA mixture of 9.23 g
2. 2
   workup.ADDITIONthe mixture is poured onto 100 ml
3. 3
   ExtraktionThe aqueous phase is extracted with 2×75 ml
4. 4
   Waschenwashed with distilled water until chloride-free
5. 5
   Trocknendried over anhydrous magnesium sulphate
6. 6
   Filtrationfiltered
7. 7
   Sonstigeevaporated in vacuo

Vorschrift

A mixture of 9.23 g. of 3-nitro-4-chloro-benzophenone, 10 ml. of ethanol and 10.3 g. of N-methyl-N-octylamine is stirred at 80° to 85° C. for 30 minutes, and then the mixture is poured onto 100 ml. of ice water. The aqueous phase is extracted with 2×75 ml. of benzene. The benzene phases are combined, washed with distilled water until chloride-free, dried over anhydrous magnesium sulphate, filtered, and evaporated in vacuo. 11.57 g. of 3-nitro-4-(N-methyl-N-octylamino)-benzophenone are obtained in the form of an oily residue. On the basis of thin layer chromatographical examination, a pure, uniform product is obtained.

Quelle