Reaktion #55599

ord-15498aed66e54dc2a770e565828a381f

Reaktionsgleichung

O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]
5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid
OCCN(CCO)CCO
triethanolamine
→
O=C([O-])c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].OCC[NH+](CCO)CCO
Tris-(2-hydroxyethyl)ammonium 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate

Edukte

O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]
5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid
OCCN(CCO)CCO
triethanolamine

Reagenzien

Keine

Lösungsmittel

COCCOC
glyme
COCCOC
glyme

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    workup.STIRRINGAfter stirring for a few hours the solvent
  2. 2
    Sonstigeis removed in vacuo
  3. 3
    Sonstigethe product is triturated repeatedly with petroleum ether (bp 30°-60° C.)
  4. 4
    Sonstigedried to a weight of 2.5 g

Vorschrift

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (3.0 g, 0.0083 mole) is dissolved in glyme (20 ml) and a solution of triethanolamine (1.35 g, 0.0091 mole) in glyme (5 ml) is added rapidly while stirring at room temperature. After stirring for a few hours the solvent is removed in vacuo, the product is triturated repeatedly with petroleum ether (bp 30°-60° C.) and dried to a weight of 2.5 g.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04220468uspto-grants-1980_09