Reaktion #554567

Reaktionsgleichung

Phosphorus oxychloride

dimethylaniline

phenanthridine

→

9-chlorophenanthridine

Ausbeute 96.0%

Lösungsmittel

H2O

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturby refluxing for 3 hours
2. 2
   Extraktionthe obtained solid was extracted with chloroform
3. 3
   Trocknenby drying with sodium sulfate
4. 4
   FiltrationAfter filtration
5. 5
   Sonstigethe filtrate was evaporated to dryness under reduced pressure
6. 6
   SonstigeThe obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%)

Vorschrift

Phosphorus oxychloride (15 ml) and dimethylaniline (0.63 ml) were added to phenanthridine (2.0 g), followed by refluxing for 3 hours. The solution was poured into H2O to generate a solid, and the obtained solid was extracted with chloroform, followed by drying with sodium sulfate. After filtration, the filtrate was evaporated to dryness under reduced pressure. The obtained solid was purified by column chromatography (eluent: chloroform) (amount: 2.1 g, yield: 96%).

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