Reaktion #55213

ord-3d33fbc7cbc74827a5ed2898b7fb5ec0

Reaktionsgleichung

CC(Br)(CCO)c1ccc(-c2ccc(F)cc2F)cc1
3-bromo-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol
CC(CCO)c1ccc(-c2ccc(F)cc2F)cc1
3-(2',4'-difluoro-4-biphenylyl)butan-1-ol
CC(=O)[O-].[K+]
potassium acetate
→
CC(=O)OC(C)(CCO)c1ccc(-c2ccc(F)cc2F)cc1
3-acetoxy-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol

Edukte

CC(Br)(CCO)c1ccc(-c2ccc(F)cc2F)cc1
3-bromo-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol
CC(CCO)c1ccc(-c2ccc(F)cc2F)cc1
3-(2',4'-difluoro-4-biphenylyl)butan-1-ol
CC(=O)[O-].[K+]
potassium acetate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstigeare reacted

Vorschrift

Analogously to Example 25 (a), 3-bromo-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol, obtained by brominating 3-(2',4'-difluoro-4-biphenylyl)butan-1-ol, and potassium acetate are reacted to give 3-acetoxy-3-(2',4'-difluoro-4-biphenylyl)butan-1-ol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151302uspto-grants-1979_04