Reaktion #55125

ord-339122cfff3945ae8de913a491173b09

Reaktionsgleichung

NCCSCc1cnccn1
2-[(2-aminoethyl)thiomethyl]pyrazine
O=C(N=C=S)c1ccccc1
benzoyl isothiocyanate
O=C(NC(=S)NCCSCc1cnccn1)c1ccccc1
N-benzoyl-N'-[2-(2-pyrazinylmethylthio)ethyl]thiourea

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

By the procedure of Example 18, 2-[(2-aminoethyl)thiomethyl]pyrazine is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-pyrazinylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-pyrazinylmethylthio)ethyl]thiourea.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151288uspto-grants-1979_04