Reaktion #55123

Reaktionsgleichung

3-chloro-5-methyl-2-pyrazinecarboxylic acid

diborane

→

3-chloro-2-hydroxymethyl-5-methylpyrazine

Reaktionsbedingungen

Vorschrift

Reduction of 3-chloro-5-methyl-2-pyrazinecarboxylic acid (prepared by alkaline hydrolysis of the methyl ester) with diborane gives 3-chloro-2-hydroxymethyl-5-methylpyrazine which, using the above procedure, yields N-methyl-N'-[2-((3-chloro-5-methyl-2-pyrazinyl)methylthio)ethyl]thiourea.

Quelle