Reaktion #55120

ord-4a997f7fe7a64c599a73e9e0d01ada42

Reaktionsgleichung

NCCSCc1ncccn1
2-[(2-aminoethyl)thiomethyl]pyrimidine
O=C(N=C=S)c1ccccc1
benzoyl isothiocyanate
O=C(NC(=S)NCCSCc1ncccn1)c1ccccc1
N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

By the procedure of Example 18, 2-[(2-aminoethyl)thiomethyl]pyrimidine is reacted with benzoyl isothiocyanate to give N-benzoyl-N'-[2-(2-pyrimidylmethylthio)ethyl]thiourea. Removing the benzoyl group by the procedure of Example 18 gives N-[2-(2-pyrimidylmethylthio)ethyl]thiourea.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151288uspto-grants-1979_04