Reaktion #55086

Reaktionsgleichung

3,4-dichloroanilinoacetic acid

ethanol

H2SO4

→

Ethyl (3,4-dichloroanilino)-acetate

Ausbeute 78.0%

Lösungsmittel

dichloroethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux
2. 2
   WaschenIt is washed with water and with dilute sodium bicarbonate
3. 3
   Sonstigedried
4. 4
   Sonstigeevaporated to dryness in vacuo
5. 5
   SonstigeThe ester is recrystallised from ethanol
6. 6
   Sonstigeis obtained in a yield of 78%

Vorschrift

A solution of 27.5 g (0.125 mol) of 3,4-dichloroanilinoacetic acid, 190 ml of dichloroethane, 15 ml (0.2 mol) of ethanol and 1.5 ml of concentrated H2SO4 is heated for 4 hours under reflux. It is washed with water and with dilute sodium bicarbonate, dried and evaporated to dryness in vacuo. The ester is recrystallised from ethanol and is obtained in a yield of 78%. It melts at 103°-104° C.

Quelle