Reaktion #55078

Reaktionsgleichung

propiophenone

ammonium carbonate

potassium cyanide

ethanol

→

5-ethyl-5-phenyl-hydantoin

Ausbeute 66.0%

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 8 hours
2. 2
   TemperaturThe solution is cooled in a mixture of ice and salt
3. 3
   Sonstigethe hydantoin precipitates
4. 4
   SonstigeThe precipitate thus obtained
5. 5
   Filtrationis filtered off
6. 6
   Waschenwashed with water

Vorschrift

A solution of 26.8 g (0.2 mol) of propiophenone, 80 g (0.8 mol) of ammonium carbonate dissolved in 300 ml of water and 28 g (0.4 mol) of potassium cyanide in 300 ml of ethanol is heated under reflux for 8 hours, whilst stirring. The solution is cooled in a mixture of ice and salt; the hydantoin precipitates. The precipitate thus obtained is filtered off and washed with water. 27.1 g (yield: 66%) of 5-ethyl-5-phenyl-hydantoin, melting at 202° C., are obtained.

Quelle