Reaktion #55003

ord-142a4a7c20964376a3661ce3b8f8c531

Reaktionsgleichung

NCCCCCN
1,5-diaminopentane
CSC(N)=[NH+]CCSCc1nc[nH]c1C.CSC(N)=[NH+]CCSCc1nc[nH]c1C.O=S(=O)([O-])[O-]
S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate
→
Cc1[nH]cnc1CSCCN=C(N)NCCCCCNC(N)=NCCSCc1nc[nH]c1C
title compound
Cc1[nH]cnc1CSCCN=C(N)NCCCCCNC(N)=NCCSCc1nc[nH]c1C
1,5-bis-[N'-(2-(5-Methyl-4-imidazolylmethylthio)ethyl)guanidino]pentane

Edukte

NCCCCCN
1,5-diaminopentane
CSC(N)=[NH+]CCSCc1nc[nH]c1C.CSC(N)=[NH+]CCSCc1nc[nH]c1C.O=S(=O)([O-])[O-]
S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The reaction of 1,5-diaminopentane (0.43 g) with S-methyl-N-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiouronium sulphate (2.52 g) by the method described in Example 5 afforded the title compound which was isolated as the dipicrate (1.8 g) m.p. 115°-120°.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151289uspto-grants-1979_04