Reaktion #54988

Reaktionsgleichung

ethyl 2-hydroxyimino-3-methoxyiminovalerate

methylamine

→

N-methyl-2-hydroxyimino-3-methoxyiminovaleramide

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.WAITto stand 18 hours
2. 2
   Sonstigeevaporated under reduced pressure (15 mm) at 50° C. water-bath temperature to dryness
3. 3
   SonstigeRecrystallization of the residue from acetonitrile

Vorschrift

a mixture of 7.6 parts ethyl 2-hydroxyimino-3-methoxyiminovalerate was mixed with 7 parts 40% aqueous methylamine solution at 25° C. and stirred till homogeneous (5 minutes). The mixture was allowed to stand 18 hours and then evaporated under reduced pressure (15 mm) at 50° C. water-bath temperature to dryness. Recrystallization of the residue from acetonitrile gave 4.3 parts of N-methyl-2-hydroxyimino-3-methoxyiminovaleramide, m.p. 168°-170° C.

Quelle