Reaktion #54985

Reaktionsgleichung

2-chloro-5-trifluoromethyl-aniline

ethoxymethylenemalononitrile

→

N-(2,2-dicyanovinyl)-2-chloro-5-trifluoromethylaniline

Ausbeute 70.0%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture is refluxed for 48 hours
2. 2
   TemperaturAfter cooling
3. 3
   Filtrationthe precipitated product is collected by filtration
4. 4
   Waschenwashed with ethanol
5. 5
   SonstigeRecrystallisation from ethanol
6. 6
   Sonstigeaffords the above product with a melting point of 166°-169° C.

Vorschrift

19.6 Parts of 2-chloro-5-trifluoromethyl-aniline and 12.2 parts of ethoxymethylenemalononitrile are dissolved in 125 parts of ethanol and the mixture is refluxed for 48 hours. After cooling, the precipitated product is collected by filtration and washed with ethanol. Recrystallisation from ethanol affords the above product with a melting point of 166°-169° C. and in a 70% yield.

Quelle