Reaktion #54967

ord-fcb3015fa3af46ecb23fab6c3a2b510a

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

5-(β-Carboethoxy-α-methyl-ethyl)-barbituric acid was treated with allyl bromide at 50° C. to afford 5-allyl-5-(β-carboethoxy-α-methyl-ethyl)-barbituric acid, m.p. 114°. Alkaline saponification of this compound afforded 5-allyl-5-(β-carboxy-α-methyl-ethyl)-barbituric acid, which was recrystallized from water, m.p. 200°.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04151268uspto-grants-1979_04