Reaktion #54875

ord-d9560b4bfd904765b7c2d2507a4e2201

Reaktionsgleichung

CCCCCC(C)(CCCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
product
CCCCCC(C)(CCCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
Ethyl 4-(4-Acetyl-4-ethoxycarbonyl-8-acetoxy-8-methyltridecyl)benzoate
CCCCCC(C=CCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
ethyl 4-(4-acetyl-4-ethoxycarbonyl-8-acetoxytridec-6-en-1-yl)benzoate
→
CCCCCC(C)(O)CCCC(CCCc1ccc(C(=O)O)cc1)C(C)=O
4-(4-Acetyl-8-hydroxy-8-methyltridecyl)benzoic Acid

Edukte

CCCCCC(C)(CCCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
product
CCCCCC(C)(CCCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
Ethyl 4-(4-Acetyl-4-ethoxycarbonyl-8-acetoxy-8-methyltridecyl)benzoate
CCCCCC(C=CCC(CCCc1ccc(C(=O)OCC)cc1)(C(C)=O)C(=O)OCC)OC(C)=O
ethyl 4-(4-acetyl-4-ethoxycarbonyl-8-acetoxytridec-6-en-1-yl)benzoate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThis compound is prepared by the method
  2. 2
    SonstigeThe title compound is purified by column chromatography on silica gel with 4% methanol in chloroform as eluant
  3. 3
    Sonstigeis obtained as a nearly colorless, viscous oil

Vorschrift

This compound is prepared by the method described in Example 3, Step C, except that an equivalent quantity of the product of Step B of the present example replaces ethyl 4-(4-acetyl-4-ethoxycarbonyl-8-acetoxytridec-6-en-1-yl)benzoate. The title compound is purified by column chromatography on silica gel with 4% methanol in chloroform as eluant and is obtained as a nearly colorless, viscous oil.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04150235uspto-grants-1979_04