Reaktion #548698

Reaktionsgleichung

aluminium chloride

cyclohexylbenzene

methyl vinyl ketone

→

4-(p-Cyclohexylphenyl)-2-butanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.DISTILLATIONwas purified by distillation, b.p

Vorschrift

To a stirred solution of aluminium chloride (0.15 mole) in cyclohexylbenzene (0.5 mole) at 10° - 15° C was added dropwise methyl vinyl ketone. The resulting mixture was left overnight at room temperature and worked up as above The crude ketone was purified by distillation, b.p. 150 - 60 (2 mm), followed by column chromatography using silica as support and petrol/ethyl acetate as eluants.

Quelle