Reaktion #548224

ord-f7e359947188445885dbe2d74e1dd436

Reaktionsgleichung

COC1=NCCCC1
O-methylvalerolactim
Cl.N[C@@H]1CCC[C@@H]1c1ccccc1
cis-2-phenylcyclopentylamine hydrochloride
COC1=NCCCCC1
O-methylcaprolactim
Cl.N[C@@H]1CCC[C@@H]1C1CCCCC1
cis-2-(cyclohexyl)cyclopentylamine hydrochloride
→
C1CCC([C@H]2CCC[C@H]2N=C2CCCCN2)CC1.Cl
desired product
C1CCC([C@H]2CCC[C@H]2N=C2CCCCN2)CC1.Cl
2-[(cis-2-Cyclohexylcyclopentyl)imino]piperidine hydrochloride

Edukte

COC1=NCCCC1
O-methylvalerolactim
Cl.N[C@@H]1CCC[C@@H]1c1ccccc1
cis-2-phenylcyclopentylamine hydrochloride
COC1=NCCCCC1
O-methylcaprolactim
Cl.N[C@@H]1CCC[C@@H]1C1CCCCC1
cis-2-(cyclohexyl)cyclopentylamine hydrochloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure of Example 23, only substituting for cis-2-phenylcyclopentylamine hydrochloride and O-methylcaprolactim, appropriate amounts of cis-2-(cyclohexyl)cyclopentylamine hydrochloride and O-methylvalerolactim respectively the desired product is obtained, M.P. 195.5°-197° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04061746uspto-grants-1977_12