Reaktion #546548

Reaktionsgleichung

3-[3-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester

biphenyl-3-ol

(2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid

→

title compound

3-{3-[3-(biphenyl-3-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe enatiomers were separated by chiral HPLC

Vorschrift

The title compound was prepared from 3-[3-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 323, Step 1) and biphenyl-3-ol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C25H26O5 [M+Na]+: 429.2.

Quelle