Reaktion #54577

Reaktionsgleichung

resorcinol

ethyl 2-naphthoylacetate

water

→

7-hydroxy-4-(2-naphthyl)coumarin

Ausbeute 26.0%

Lösungsmittel

sulphuric acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto give a yellow gum
2. 2
   WaschenThe gum was washed several times with water
3. 3
   workup.DISSOLUTIONthen dissolved in ethanol
4. 4
   workup.ADDITIONdiluted with water

Vorschrift

A mixture of resorcinol (11.0 g, 0.1 mole) and ethyl 2-naphthoylacetate (24.2 g, 0.1 mole) in concentrated sulphuric acid (50 ml) was stirred at room temperature for 5 days then poured into water to give a yellow gum. The gum was washed several times with water then dissolved in ethanol and diluted with water to give 7-hydroxy-4-(2-naphthyl)coumarin as a fine pale brown precipitate in 26% yield.

Quelle