Reaktion #544641

Reaktionsgleichung

octan-1-one

hydroxylammonium chloride

sodium acetate

→

pale yellow solid

octan-1-one oxime

Lösungsmittel

ethanol

water

H2O

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturAfter refluxing for 7 h
2. 2
   Filtrationthe resulting white solid is filtered off
3. 3
   Waschenwashed with water
4. 4
   workup.DISSOLUTIONdissolved in tetrahydrofurane (THF)
5. 5
   TrocknenAfter drying this THF solution
6. 6
   Sonstigeover anhydrous MgSO4, condensation under reduced pressure

Vorschrift

To hydroxylammonium chloride (0.39 g; 5.57 mmol) and sodium acetate (0.54 g; 6.57 mmol) dissolved in 5 ml of water is added 1-(6-Benzoyl-9-ethyl-9.H.-carbazol-3-yl)-octan-1-one (2.14 g; 5.03 mol) in 15 ml of ethanol. After refluxing for 7 h, H2O is added to the reaction mixture, the resulting white solid is filtered off, washed with water and dissolved in tetrahydrofurane (THF). After drying this THF solution over anhydrous MgSO4, condensation under reduced pressure affords 2.16 g of a pale yellow solid (97%).

Quelle