Reaktion #54459

Reaktionsgleichung

potassium carbonate

triacetonamine

ethyl cyanoacetate

ammonium acetate

→

Ethyl 2,2,6,6-tetramethyl-4-piperidinylidene-cyanoacetate

Lösungsmittel

benzene

benzene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturunder reflux for 1.5 hours under a water separator
2. 2
   Trocknenthe organic phase is dried over sodium sulphate

Vorschrift

155 g (1 mol) of triacetonamine, 113 g of ethyl cyanoacetate, 300 ml of benzene and 31 g of ammonium acetate are kept under reflux for 1.5 hours under a water separator. The benzene phase is treated with 50% of potassium carbonate, the organic phase is dried over sodium sulphate and the benzene is then stripped off in vacuo. Ethyl 2,2,6,6-tetramethyl-4-piperidinylidene-cyanoacetate is obtained as an oily residue.

Quelle