Reaktion #54454
ord-947d44843c3f4b7fbab1d2263be8b0ed
Reaktionsgleichung
propargyl alcohol
formaldehyde
diethylamine
potassium iodide
sulfuric acid
→
1-diethylaminobut-2-yn-4-ol
Ausbeute 86.0%
Reagenzien
Lösungsmittel
Reaktionsbedingungen
Temperatur
92°CELSIUS
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
204 parts by weight of aqueous 55% strength propargyl alcohol, 250 parts by weight of 30% strength aqueous formaldehyde, 161 parts by weight of diethylamine, 1.4 parts by weight of copper sulfate, 2 parts by weight of potassium iodide, 50 parts by weight of water and 115 parts by weight of concentrated sulfuric acid are mixed and brought to pH 5. The mixture is heated for 5 hours at 92° C. and worked up as described. 242 parts by weight of 1-diethylaminobut-2-yn-4-ol are obtained, corresponding to a yield of 86%.